Phosphorus pentachloride → 2-chloro-6-fluoro-N-(4-iodophenyl)benzenecarbohydrazonoyl chloride

Participants

Reaction Steps

The title compound was prepared according to the procedure described in step-2 of Intermediate-1 using (1E)-1-(2-chloro-6-fluorobenzylidene)-2-(4-iodophenyl)hydrazine (1.2 g, 3.20 mmol), PCl5 (0.990 g, 4.8 mmol) and benzene (20 mL) to afford 1.0 g of desired product. 1H NMR (300 MHz, DMSO d6): δ 7.00 (d, J=8.7 Hz, 2H), 7.41 (d, J=8.7 Hz, 1H), 7.48-7.60 (m, 4H), 10.22 (s, 1H).

Provenance & Evidence