化工社化工社 化学情報印刷レポート · 研究参考用
Potassium Carbonate → Benzenecarboximidamide, N-hydroxy-3,5-dimethoxy-
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | 1-(Cyanomethyl)-3,5-dimethoxybenzene | HCID 29482 | — |
| 反応物 | Hydroxyamine hydrochloride | HCID 443297 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | Benzenecarboximidamide, N-hydroxy-3,5-dimethoxy- | HCID 2731154 | 33.3% |
反応手順
The title compound was prepared according to the procedure described in Intermediate-19 by using 3,5-dimethoxy benzonitrile (1.00 g, 6.13 mmol), hydroxylamine HCl (0.634 g, 9.23 mmol) and potassium carbonate (2.53 g, 18.40 mmol), ethanol (20 mL) to afford 0.400 g of desired product. 1H NMR (300 MHz, DMSO d6): δ 3.75 (s, 6H), 5.79 (s, 2H), 6.49 (s, 1H), 6.84 (s, 2H), 9.62 (br s, 1H); MS (m/z): 197.11 (M+H)+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09096545B2 |
| 出典データセット | uspto-grants-2015_08 |
| ORD ID | ord-bfce297d95194f58a0d28f0fdfecf792 |
| 出典メモ | uspto-grants-2015_08 |