HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Dichloropyridine → (E)-1-(6-chloropyridin-2-yl)-2-styryl-1H-benzimidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Dichloropyridine | HCID 16989 | — |
| Reactant | 2-(2-Phenylethenyl)-1h-benzimidazole | HCID 242965 | — |
| Reactant | (E)-1-(2-pyridyl)-2-styryl-1H-benzimidazole | HCID 9796241 | — |
| Product | (E)-1-(6-chloropyridin-2-yl)-2-styryl-1H-benzimidazole | HCID 22736737 | — |
Reaction Steps
Free base of the titled compound was prepared from 2-styryl-1H-benzimidazole and 2,6-dichloropyridine according to the preparation of (E)-1-(2-pyridyl)-2-styryl-1H-benzimidazole (Example 1, method B). MW: 331.81; mp: 122.0-123.0° C.; 1H-NMR (DMSO) δ: 8.22 (1H, t, J=7.9 Hz), 7.91 (1H, d, J=16.1 Hz), 7.79-7.72 (3H, m), 7.67-7.63 (2H, m), 7.50-7.47 (1H, m), 746-7.28 (5H, m), 7.23 (1H, d, J=16.1 Hz).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06713482B2 |
| Source dataset | uspto-grants-2004_03 |
| ORD ID | ord-816abe7237094fe3ac23eee9419270c4 |
| Source note | uspto-grants-2004_03 |