HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → 3-Methoxy-4-nitrobenzoyl isocyanate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 3-Methoxy-4-nitrobenzamide | HCID 11063338 | — |
| Solvent | 1,2-Dichloroethane | HCID 11 | — |
| Product | 3-Methoxy-4-nitrobenzoyl isocyanate | HCID 90018902 | 88.3% |
Reaction Steps
To a solution of 3-methoxy-4-nitrobenzamide (1.00 g, 5.10 mmol) in EDC (10 mL) was added oxalyl chloride (0.64 g, 6.12 mmol). The reaction mass was refluxed for 24 h. Excess of solvent was removed under vacuum to afford 1.0 g of desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09096545B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-3cb2c03939df4e6ea2fdfa3c4c31c991 |
| Source note | uspto-grants-2015_08 |