Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ammonia → 3-((2,2,2-Trifluoroacetamido)methyl)-2,6-dimethylbenzamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ammonia | HCID 222 | — |
| 반응물 | Oxalyl chloride | HCID 65578 | — |
| 반응물 | 2,6-Dimethyl-3-((2,2,2-trifluoroacetamido)methyl)benzoic acid | HCID 86692227 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 3-((2,2,2-Trifluoroacetamido)methyl)-2,6-dimethylbenzamide | HCID 90019133 | — |
반응 단계
The title compound was prepared according to the procedure described in step-2 of Intermediate-26 by using 3((2,2,2-trifluoroacetamido)methyl)-2,6-dimethylbenzoic acid (1.0 g), oxalyl chloride (1.0 mL), THF (50 mL) and ammonia gas to afford 0.800 g of the desired product.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09096545B2 |
| 출처 데이터셋 | uspto-grants-2015_08 |
| ORD ID | ord-61304cec033b4ec8b395ff9e9289a87d |
| 출처 메모 | uspto-grants-2015_08 |