HCID 58481568, compound → HCID 58481541, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 2-(4-fluoro-2,6-dimethylphenyl)cyclopent-4-ene-1,3-dione (2.9 g, 13.3 mmol) in acetic acid (116 ml) is added zinc powder (6 g, 91.7 mmol) at 25-30° C. The resulting solution is stirred at 25-30° C. for 16 hours. The reaction mixture is then filtered through diatomaceous earth and concentrated to give a crude product (2.9 g) which is used for the next step.

Provenance & Evidence