HCID 57779641, compound → HCID 57779539, compound

HRID 509185Notes

Reaction equation

HRID 509185 reaction equation
[NH2:1][C:2]1[CH:7]=[C:6]([C:8]2[S:9][CH:10]=[CH:11][CH:12]=2)[CH:5]=[CH:4][C:3]=1[NH:13][C:14](=O)[CH:15]([C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1)[C:16]([O:18][CH2:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)=[O:17]>CC(O)=O>[C:26]1([CH:15]([C:14]2[NH:1][C:2]3[CH:7]=[C:6]([C:8]4[S:9][CH:10]=[CH:11][CH:12]=4)[CH:5]=[CH:4][C:3]=3[N:13]=2)[C:16]([O:18][CH2:19][C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)=[O:17])[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1

Participants

3

Reactant 1

HCID 57779641HCID 57779641, compound

Product 1

HCID 57779539HCID 57779539, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Conditions

Temperature
100 °C

Procedure

AcOH (3 mL) was added to compound 32 (463 mg, 1.04 mmol) and the reaction heated at 100° C. for 30 min. The solvent was evaporated under reduced pressure.

Workup

  1. customThe solvent was evaporated under reduced pressure

Sources & evidence

ORD record
ord-16aa53b1c00948df8714fcc6a04a91d8
Source dataset
uspto-grants-2015_08
Patent number
US09096565B2

Reaction notes

Loading…