化工社化工社 化学情報印刷レポート · 研究参考用
Cinnamoyl Chloride → (E)-6-Methyl-1-(2-pyridyl)-2-styryl-1H-benzimidazole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Cinnamoyl Chloride | HCID 5354261 | — |
| 反応物 | (E)-1-(2-pyridyl)-2-styryl-1H-benzimidazole | HCID 9796241 | — |
| 反応物 | 2-amino-5-methyl-N-(2-pyridyl)aniline | HCID 22736708 | — |
| 生成物 | (E)-6-Methyl-1-(2-pyridyl)-2-styryl-1H-benzimidazole | HCID 22736763 | — |
反応手順
The titled compound was prepared from 2-amino-5-methyl-N-(2-pyridyl)aniline and (E)-cinnamoyl chloride according to the preparation of (E)-1-(2-pyridyl)-2-styryl-1H-benzimidazole (Example 1, method A). MW: 311.39; mp: 164.0-164.9° C.; 1H-NMR (CDCl3) δ: 8.80-8.76 (1H, m), 8.03-7.92 (2H, m), 7.71 (1H, d, J=8.1 Hz), 7.54-7.42 (4H, m), 7.38-7.23 (4H, m), 7.19-7.14 (1H, m), 7.11 (1H, d, J=16.1 Hz), 2.46 (3H, s).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06713482B2 |
| 出典データセット | uspto-grants-2004_03 |
| ORD ID | ord-dedc25f6e8104377816b60455501a15a |
| 出典メモ | uspto-grants-2004_03 |