HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine hydrate (1:1) → 4-Cyanobenzohydrazide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | Methyl 4-cyanobenzoate | HCID 70791 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-Cyanobenzohydrazide | HCID 456732 | — |
Reaction Steps
To a solution of 4-cyano-benzoic acid methyl ester (1.0 g, 13 mmol) in 30 mL of MeOH was added 3 mL of H2NNH2.H2O. The mixture was stirred at ambient temperature for 16 h. The solid was collected and washed with CH3OH to give 4-cyano-benzoic acid hydrazide 9 as a solid. Yield: 0.8 g, 80%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09096587B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-98e48761664846dd866247b36521887e |
| Source note | uspto-grants-2015_08 |