HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-bromo-1H-pyrrolo[2,3-b]pyridine → [5-(5-Bromo-1H-pyrrolo[2,3-b]pyridin-3-ylmethyl)-pyridin-2-yl]-(6-methoxy-pyridin-3-ylmethyl)-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-bromo-1H-pyrrolo[2,3-b]pyridine | HCID 10307932 | — |
| Reactant | (5-Formyl-pyridin-2-yl)-(6-methoxy-pyridin-3-ylmethyl)-carbamic acid tert-butyl ester | HCID 57619225 | — |
| Product | [5-(5-Bromo-1H-pyrrolo[2,3-b]pyridin-3-ylmethyl)-pyridin-2-yl]-(6-methoxy-pyridin-3-ylmethyl)-amine | HCID 67200583 | — |
Reaction Steps
[5-(5-Bromo-1H-pyrrolo[2,3-b]pyridin-3-ylmethyl)-pyridin-2-yl]-(6-methoxy-pyridin-3-ylmethyl)-amine P-2017 was prepared in two steps from 5-bromo-1H-pyrrolo[2,3-b]pyridine 152 and (5-formyl-pyridin-2-yl)-(6-methoxy-pyridin-3-ylmethyl)-carbamic acid tert-butyl ester 153 as shown in Scheme 21.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09096593B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-694e0843b8964be88430ebbdad797393 |
| Source note | uspto-grants-2015_08 |