反应详情

300 mg (0.785 mmol) of the compound from example 39A were initially charged in pyridine (35 ml), then 119 mg of palladium (10% on charcoal) were added and the mixture was hydrogenated at standard hydrogen pressure overnight. The reaction mixture was filtered through kieselguhr and washed through with ethanol, and the filtrate was concentrated. This gave 219 mg (92% purity, 73% of theory) of the title compound in solid form.

1. filtrationThe reaction mixture was filtered through kieselguhr
2. washwashed through with ethanol
3. concentrationthe filtrate was concentrated