Diisopropylamine → HCID 66634914, compound

Participants

Reaction Conditions

Reaction Steps

15.00 g (38.99 mmol) of the compound from example 79A were dissolved in 200 ml of dioxane, 6.98 g (40.94 mmol) of 2,4-dimethoxybenzylamine and 5.54 g (42.88 mmol) of N,N-diisopropylamine were added and the mixture was stirred at 85° C. for 1 h. After cooling, the mixture was filtered and the filtrate was concentrated on a rotary evaporator and the residue was dried under high vacuum. The residue was crushed with a mortar and pestle, stirred with 250 ml of water, filtered off with suction and dried under high vacuum. 19.96 g (89% of theory) of the title compound were obtained.

Provenance & Evidence