Iodine → HCID 87085197, compound

Participants

Reaction Conditions

Reaction Steps

1.788 g (3.364 mmol) of the compound from example 96A were initially charged in 20 ml of 1,2-dimethoxyethane and then admixed at RT with 873 mg (3.364 mmol) of cesium iodide, 426 mg (1.682 mmol) of iodine and 192 mg (1.009 mmol) of copper(I) iodide. After addition of 2.961 ml of isopentyl nitrite, the mixture was heated to 60° C. overnight. After cooling, a precipitate was filtered off and washed with ethyl acetate. Subsequently, water was added to the precipitate, the mixture was stirred and then the precipitate was again filtered off with suction and washed with a little water and acetonitrile. 0.373 g (17% of theory) of the title compound were obtained after drying under high vacuum.

Provenance & Evidence