HCID 56593553, compound → HCID 56847714, compound

Participants

Reaction Conditions

Reaction Steps

Under an argon atmosphere, 2.100 g (4.282 mmol) of the compound from example 15A were dissolved in 235 ml of tetrahydrofuran and cooled to 0° C., and 10.705 ml (10.705 mmol) of a 1N solution of bis(trimethylsilyl)sodium amide in tetrahydrofuran were added dropwise. The mixture was stirred at 0° C. for 2 h and then at RT for 16 h. The tetrahydrofuran was partly concentrated in an argon stream and the precipitate was filtered off. 1.290 g of the title compound were obtained (66% of theory).

Provenance & Evidence