Methanol → HCID 66635144, compound

Participants

Reaction Conditions

Reaction Steps

120 mg (0.263 mmol) of the carbamate from example 51A were initially charged in methanol (5.0 ml), 100 μl (0.525 mmol) of sodium methoxide solution (25% w/w in methanol) were added and the mixture was stirred at 65° C. for 30 min. The solvent was removed under reduced pressure, the residue was separated by means of preparative HPLC and the product fractions were concentrated. This gave 53.1 mg (48% of theory) of the title compound in solid form.

Provenance & Evidence