Hydrochloric Acid → HCID 90169896, compound

Participants

Reaction Steps

579 mg (approx. 0.887 mmol, 79% purity) of the compound from example 98A were dissolved 10 ml of dioxane and then admixed with 4 ml of a 4N solution of hydrogen chloride in dioxane and stirred at RT for 0.5 h. This was followed by concentration to dryness. After purification by means of preparative HPLC (acetonitrile:water (+0.05% formic acid) gradient), this gave 168 mg (41% of theory) of the title compound.

Provenance & Evidence