HRID510210
反应详情
EQUATION
反应方程式
REACTANTS
反应物
PRODUCTS
生成物
AUXILIARIES
试剂、催化剂与溶剂
PROCEDURE
实验过程
To a solution of N2-[5-(5-amino-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-3-yl]-N-(2,2,2-trifluoroethyl)valinamide 5-1b (50 mg, 0.093 mmol) in DCM (2 mL) and pyridine (0.5 mL) was added methanesulfonyl chloride (7.62 μl, 0.098 mmol) and mixture was stirred for 18 h. The residue 5-3a was used without further purification. MS APCI: [M+H]+ m/z=615.1.
WORKUP
后处理
- customThe residue 5-3a was used without further purification