2,3-dihydro-4H-1,4-benzothiazin-4-amine → 1,2,8,9,10,11-hexahydro-7H-azepino[4,5-b][1,4]thiazino[2,3,4-hi]indole hydrochloride

HRID 51046Notes

Reaction equation

HRID 51046 reaction equation
[S:1]1[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[N:4](N)[CH2:3][CH2:2]1.[ClH:12].[NH:13]1[CH2:19][CH2:18][CH2:17][C:16](=O)[CH2:15][CH2:14]1>>[ClH:12].[CH2:3]1[N:4]2[C:5]3[C:10]([C:17]4[CH2:18][CH2:19][NH:13][CH2:14][CH2:15][C:16]=42)=[CH:9][CH:8]=[CH:7][C:6]=3[S:1][CH2:2]1

Participants

3

Reactant 2

HCID 218596142,3-dihydro-4H-1,4-benzothiazin-4-amineHCID 22021728Azepan-4-one hydrochloride

Product 1

HCID 225037401,2,8,9,10,11-hexahydro-7H-azepino[4,5-b][1,4]thiazino[2,3,4-hi]indole hydrochloride

Procedure

1,2,8,9,10,11-Hexahydro-7H-azepino[4,5-b][1,4]thiazino[2,3,4-hi]indole hydrochloride was prepared from 2,3-dihydro-4H-1,4-benzothiazin-4-amine and hexahydro-4H-azepin-4-one hydrochloride following the procedure of example 471, step A to give the 1,2,8,9,10,11-hexahydro-7H-azepino[4,5-b][1,4]thiazino[2,3,4-hi]indole hydrochloride

Sources & evidence

ORD record
ord-b66ec9c446694bdbbe1b6ffc01353aa3
Source dataset
uspto-grants-2004_03
Patent number
US06713471B1

Reaction notes

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