6-Chloro-2-methyl-3-nitropyridine → HCID 59613057, compound

HRID 510482Notes

Reaction equation

HRID 510482 reaction equation
Cl[C:2]1[N:7]=[C:6]([CH3:8])[C:5]([N+:9]([O-:11])=[O:10])=[CH:4][CH:3]=1.[F:12][C:13]1([F:17])[CH2:16][NH:15][CH2:14]1>>[F:12][C:13]1([F:17])[CH2:16][N:15]([C:2]2[N:7]=[C:6]([CH3:8])[C:5]([N+:9]([O-:11])=[O:10])=[CH:4][CH:3]=2)[CH2:14]1

Participants

3

Reactant 2

HCID 2531236-Chloro-2-methyl-3-nitropyridineHCID 27582483,3-Difluoroazetidine

Product 1

HCID 59613057HCID 59613057, compound

Procedure

Prepared from 6-chloro-2-methyl-3-nitropyridine and 3,3-difluoroazetidine following the method used to prepare Intermediate 49. LCMS (ES+) 230 (M+H)+, RT 2.57 minutes (method 1).

Workup

  1. customLCMS (ES+) 230 (M+H)+, RT 2.57 minutes (method 1)

Sources & evidence

ORD record
ord-347f3edfecc14331a0b68b64e12d53c4
Source dataset
uspto-grants-2015_08
Patent number
US09096614B2

Reaction notes

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