6-Chloro-2-methyl-3-nitropyridine → HCID 89559048, compound

HRID 510485Notes

Reaction equation

HRID 510485 reaction equation
Cl[C:2]1[N:7]=[C:6]([CH3:8])[C:5]([N+:9]([O-:11])=[O:10])=[CH:4][CH:3]=1.[F:12][CH:13]1[CH2:17][CH2:16][NH:15][CH2:14]1>>[F:12][CH:13]1[CH2:17][CH2:16][N:15]([C:2]2[N:7]=[C:6]([CH3:8])[C:5]([N+:9]([O-:11])=[O:10])=[CH:4][CH:3]=2)[CH2:14]1

Participants

3

Reactant 2

HCID 2531236-Chloro-2-methyl-3-nitropyridineHCID 3744989Pyrrolidine, 3-fluoro-

Product 1

HCID 89559048HCID 89559048, compound

Procedure

The title compound was prepared from 6-chloro-2-methyl-3-nitropyridine and 3-fluoropyrrolidine following the method used to prepare Intermediate 51. LCMS (ES+) 226 (M+H)+, RT 2.847 minutes (method 1).

Workup

  1. customLCMS (ES+) 226 (M+H)+, RT 2.847 minutes (method 1)

Sources & evidence

ORD record
ord-0ec4ea6ff77d4ad28f3195f50320851e
Source dataset
uspto-grants-2015_08
Patent number
US09096614B2

Reaction notes

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