3-Chloro-6-nitrotoluene → HCID 77982939, compound

HRID 510486Notes

Reaction equation

HRID 510486 reaction equation
Cl[C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[C:4]([CH3:11])[CH:3]=1.[F:12][CH:13]1[CH2:17][CH2:16][NH:15][CH2:14]1>>[F:12][CH:13]1[CH2:17][CH2:16][N:15]([C:2]2[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[C:4]([CH3:11])[CH:3]=2)[CH2:14]1

Participants

3

Reactant 2

HCID 793293-Chloro-6-nitrotolueneHCID 3744989Pyrrolidine, 3-fluoro-

Product 1

HCID 77982939HCID 77982939, compound

Procedure

Prepared from 4-chloro-2-methyl-1-nitrobenzene and 3-fluoropyrrolidine following the method used to prepare Intermediate 49. LCMS (ES+) 224.90 (M+H)+, RT 2.90 minutes (method 1).

Workup

  1. customLCMS (ES+) 224.90 (M+H)+, RT 2.90 minutes (method 1)

Sources & evidence

ORD record
ord-2bddc5d149c0485eb1459d9d8b63e2fe
Source dataset
uspto-grants-2015_08
Patent number
US09096614B2

Reaction notes

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