HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(Phenylmethyl)-1H-indazol-5-amine → (1-benzyl-1H-indazol-5-yl)-(6-iodo-7-fluoroquinazolin-4-yl)-amine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(Phenylmethyl)-1H-indazol-5-amine | HCID 212069 | — |
| Reactant | 4-Chloro-7-fluoro-6-iodoquinazoline | HCID 21952006 | — |
| Product | (1-benzyl-1H-indazol-5-yl)-(6-iodo-7-fluoroquinazolin-4-yl)-amine hydrochloride | HCID 21952244 | — |
Reaction Steps
Prepared according to Procedure A from 1-benzyl-1H-indazol-5-ylamine and 4-chloro-6-iodo-7-fluoroquinazoline. δH NMR (400 MHz, DMSO-d6): 11.55(s, 1H), 9.41(d, 1H), 8.8(s, 1H), 8.18(s, 1H), 8.05(d, 1H), 7.78(d, 1H), 7.69(d, 1H), 7.61(m, 1H), 7.29(m, 2H), 7.23(m, 3H), 5.67(s, 2H). ESI-MS m/z 496(M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06713485B2 |
| Source dataset | uspto-grants-2004_03 |
| ORD ID | ord-354898f2a1764775b4f31b1140ca28bd |
| Source note | uspto-grants-2004_03 |