2-Amino-5-fluoro-N-methylbenzamide → 2-amino-4-fluoro-N-methylbenzamide

HRID 511283Notes

Reaction equation

HRID 511283 reaction equation
NC1C=CC(F)=CC=1C(NC)=O.[F:13][C:14]1[CH:23]=[CH:22][C:17]([C:18]([NH:20][CH3:21])=[O:19])=[C:16]([N+:24]([O-])=O)[CH:15]=1>>[NH2:24][C:16]1[CH:15]=[C:14]([F:13])[CH:23]=[CH:22][C:17]=1[C:18]([NH:20][CH3:21])=[O:19]

Participants

3

Reactant 2

HCID 431325582-Amino-5-fluoro-N-methylbenzamideHCID 671150044-fluoro-N-methyl-2-nitrobenzamide2×

Product 1

HCID 569516612-amino-4-fluoro-N-methylbenzamide

Procedure

The title compound was prepared using the procedure from Compound 102A with 4-Fluoro-N-methyl-2-nitrobenzamide (Compound 103B). MS (ES+): m/z 169.07 [MH+] (TOF, polar).

Sources & evidence

ORD record
ord-1a280125a41b4646b88e61e8092867eb
Source dataset
uspto-grants-2015_08
Patent number
US09096624B2

Reaction notes

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