HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluoro-2-nitrobenzoic acid → 4-fluoro-N-methyl-2-nitrobenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluoro-2-nitrobenzoic acid | HCID 2737416 | — |
| Reactant | 5-Fluoro-N-methyl-2-nitrobenzamide | HCID 44203077 | — |
| Product | 4-fluoro-N-methyl-2-nitrobenzamide | HCID 67115004 | — |
Reaction Steps
The title compound was prepared using the procedure from 5-fluoro-N-methyl-2-nitrobenzamide (Compound 102B) with the commercially available 4-fluoro-2-nitrobenzoic acid. 1H NMR (CDCl3, 400 MHz): δ=3.04 (d, J=4.80 Hz, 3 H), 5.88 (br. s., 1 H), 7.39 (ddd, J=8.46, 7.45, 2.53 Hz, 1 H), 7.55 (dd, J=8.59, 5.31 Hz, 1 H), 7.78 (dd, J=8.34, 2.53 Hz, 1 H). MS (ES+): m/z 199.05 [MH+] (TOF, polar).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09096624B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-37675c302e5f45518cfaed89cec6f5b1 |
| Source note | uspto-grants-2015_08 |