HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(Chloromethyl)-1-fluoro-3-methoxy-2-nitrobenzene → Diethyl (3-fluoro-5-methoxy-4-nitrobenzyl)phosphonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(Chloromethyl)-1-fluoro-3-methoxy-2-nitrobenzene | HCID 67254475 | — |
| Reactant | Diethyl 3-chloro-4-nitrobenzylphosphonate | HCID 86654007 | — |
| Product | Diethyl (3-fluoro-5-methoxy-4-nitrobenzyl)phosphonate | HCID 86654023 | — |
Reaction Steps
The title compound was prepared using the procedure from Compound 104C (Diethyl (3-chloro-4-nitrobenzyl)phosphonate) with 5-(chloromethyl)-1-fluoro-3-methoxy-2-nitrobenzene (Compound 146C). 1H NMR (CDCl3, 400 MHz): δ=1.31 (t, J=7.07 Hz, 6 H), 3.11-3.18 (m, 2 H), 3.94 (s, 3 H), 4.07-4.13 (m, 4 H), 6.77 (dt, J=9.79, 1.93 Hz, 1 H), 6.82 (s, 1 H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09096624B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-08d8cc7397504302af4b88603decb05a |
| Source note | uspto-grants-2015_08 |