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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 51135Generated: October 28, 2026

Hydrochloric Acid → HCID 54394484, compound

https://huagongshe.com/reaction/51135

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant(1-Benzyl-1H-indazol-5-yl)-[7-(5-(1,3-dioxolan-2-yl)-furan-2-yl)quinazolin-4-yl]amine HydrochlorideHCID 21951956—
SolventTetrahydrofuranHCID 8028—
ProductHCID 54394484HCID 54394484—

Reaction Steps

Prepared according to Procedure C from (1-benzyl-1H-indazol-5-yl)-[7-(5-(1,3-dioxolan-2-yl)furan-2-yl)quinazolin-4-yl]-amine hydrochloride (0.27 g) stirred in THF:2N HCl (2:1, 15 ml) at 20° C. for 1 hour. Filtration gave 5-[4-(1-benzyl-1H-indazol-5-ylamino)-quinazolin-7-yl]-furan-2-carbaldehyde, which was not further characterised.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06713485B2
Source datasetuspto-grants-2004_03
ORD IDord-9539b6f4c9c9497e91b7922c1838153e
Source noteuspto-grants-2004_03