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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 511377Generated: October 28, 2026

2-Fluoro-6-nitrobenzoic acid → 2-fluoro-N-methyl-6-nitrobenzamide

https://huagongshe.com/reaction/511377

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluoro-6-nitrobenzoic acidHCID 603758—
Reactant5-Fluoro-N-methyl-2-nitrobenzamideHCID 44203077—
Product2-fluoro-N-methyl-6-nitrobenzamideHCID 67255708—

Reaction Steps

The title compound was prepared according to the procedure for Compound 102B (5-fluoro-N-methyl-2-nitrobenzamide) using 2-fluoro-6-nitrobenzoic acid. 1H NMR (CDCl3, 400 MHz): δ=3.09 (d, J=5.05 Hz, 3 H), 7.45 (td, J=8.34, 1.01 Hz, 1 H), 7.56 (td, J=8.27, 5.43 Hz, 1 H), 7.94 (dt, J=8.08, 1.01 Hz, 1 H). MS (ES+): m/z 199.05 [MH+] (TOF, polar).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09096624B2
Source datasetuspto-grants-2015_08
ORD IDord-fbf04446a305463a91a677b3fc941ae5
Source noteuspto-grants-2015_08