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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 511485Generated: October 28, 2026

N-Methylethylamine → 7-amino-4-{4-[ethyl(methyl)amino]cyclohexyl}-2-methyl-2,3-dihydro-1H-isoindol-1-one

https://huagongshe.com/reaction/511485

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-MethylethylamineHCID 12219—
Reactant7-amino-4-[4-(dimethylamino)cyclohexyl]-2-methyl-2,3-dihydro-1H-isoindol-1-oneHCID 67254285—
Reactant7-amino-2-methyl-4-(4-oxocyclohexyl)-2,3-dihydro-1H-isoindol-1-oneHCID 67256125—
Product7-amino-4-{4-[ethyl(methyl)amino]cyclohexyl}-2-methyl-2,3-dihydro-1H-isoindol-1-oneHCID 67255789—

Reaction Steps

The title product was prepared according to the procedure for Compound 233A using 7-amino-2-methyl-4-(4-oxocyclohexyl)-2,3-dihydro-1H-isoindol-1-one and ethyl-methylamine. Used without purification in the next step.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09096624B2
Source datasetuspto-grants-2015_08
ORD IDord-4b24225babb14f7ab11d73813e9f8f7a
Source noteuspto-grants-2015_08