反应详情

温度

90 °C

To a stirred solution of leucine t-butyl ester (10 g) in toluene (100 mL) is added thiophene-2-carboxaldehyde (5.0 mL) and the mixture is heated to 90° C. for 2 hours. The mixture was cooled, washed with water, dried over magnesium sulfate, filtered, and evaporated to an oil (14.5 g).

1. temperatureThe mixture was cooled
2. washwashed with water
3. dry with materialdried over magnesium sulfate
4. filtrationfiltered
5. customevaporated to an oil (14.5 g)