HCID 86702733, compound → HCID 86702734, compound

Participants

Reaction Steps

20 mg of palladium on activated carbon (10%) are added to 1.10 g (2.72 mmol) of 6-(benzyloxy)-5-(2,6-diethyl-4-methylphenyl)-4-oxo-1,2,3,3a,4,6a-hexahydropentalene-2-carbaldehyde in 20 ml of methanol, and the mixture is hydrogenated (15 bar, room temperature) for 20 h. The filtration and concentration on a rotary evaporator give 0.82 g (97%) of the title compound (I-a-3, isomer ratio according to 1H-NMR 4:1).

Provenance & Evidence