Triethylamine → HCID 86702739, compound

Participants

Reaction Steps

0.104 g (0.31 mmol) of 5-(2,6-diethyl-4-methylphenyl)-6-hydroxy-4-oxo-1,2,3,3a,4,6a-hexahydropentalene-2-carbaldehyde O-methyloxime (compound I-a-13 according to the invention), 0.040 g (0.34 mmol) of pivaloyl chloride and 92 mg (0.91 mmol) of triethylamine in 8 ml of dichloromethane are stirred at room temperature for 2 h. The mixture is poured onto ice, taken up in dichloromethane, washed with water, dried (magnesium sulphate) and concentrated using a rotary evaporator. Chromatography on silica gel (mobile phase ethyl acetate/hexane v:v=25:75) gives 107 mg of the title compound as a colourless oil.

Provenance & Evidence