HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloride methanol → HCID 67291349, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloride methanol | HCID 21893726 | — |
| Reactant | HCID 68450007 | HCID 68450007 | — |
| Product | HCID 67291349 | HCID 67291349 | 49% |
Reaction Steps
(R)-N-((R)-1-(5-(cyclopropylmethoxy)pyridin-2-yl)ethyl)-2-methylpropane-2-sulfinamide (3.2 g, 10.9 mmol) was dissolved in 10N HCl/MeOH (50 mL). The mixture was stirred at room temperature for 3 hours. The mixture was concentrated by N2-flow to give the white precipitate. The solid was collected by filtration and washed with diisopropyl ether to give 3.2 g (49% yield) of the title compound as a white solid:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09101616B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-d18ce5af483e4cf0a0fa2e753328258e |
| Source note | uspto-grants-2015_08 |