Boron tribromide → HCID 66930887, compound

HRID 511963Notes

Reaction equation

HRID 511963 reaction equation
C[O:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][CH2:10][CH2:11][CH2:12][CH2:13]OC2C=CC=CC=2)=[CH:5][CH:4]=1.B(Br)(Br)[Br:22]>C(Cl)Cl>[Br:22][CH2:13][CH2:12][CH2:11][CH2:10][CH2:9][C:6]1[CH:7]=[CH:8][C:3]([OH:2])=[CH:4][CH:5]=1

Participants

4

Reactant 2

HCID 25134Boron tribromideHCID 54481191HCID 54481191, compound

Product 1

HCID 66930887HCID 66930887, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

5-Bromo-1-(4-hydroxy-phenyl)-pentane (9.4) was synthesized as in 9.1 using 8.4 (3.43 g, 12.7 mmol) in anhydrous CH2Cl2 (120 mL), and BBr3 (1M solution in CH2Cl2, 32 mL, 32 mmol). The title compound (9.4) was isolated as a viscous liquid after purification by flash column chromatography (2.84 g, 92% yield).

Sources & evidence

ORD record
ord-b54ba563003a4f90898aab991c735ef5
Source dataset
uspto-grants-2015_08
Patent number
US09102622B2

Reaction notes

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