HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene → HCID 25017079, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene | HCID 241 | — |
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | HCID 71512042 | HCID 71512042 | — |
| Product | HCID 25017079 | HCID 25017079 | 39% |
| Product | HCID 25017341 | HCID 25017341 | — |
Reaction Steps
7-(3-Benzyloxy-phenyl)-heptanesulfonyl chloride (12.2) was synthesized as described in 12.1 using 11.2 (0.42 g, 1.1 mmol) and thionyl chloride (0.36 g, 3 mmol) in benzene (9 mL)/DMF (1 mL). Purification by flash column chromatography on silica gel gave the title compound (0.163 g, 39% yield from 10.2) as a viscous liquid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102622B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-d2a0872a3c8944799639332dfb8141c5 |
| Source note | uspto-grants-2015_08 |