2-Methylbenzoic acid → 2-Methyl-N-(1-pyridin-3-yl-cyclopentylmethyl)-benzamide

HRID 512215Notes

Reaction equation

HRID 512215 reaction equation
[CH3:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[N:11]1[CH:16]=[CH:15][CH:14]=[C:13]([C:17]2([CH2:22][NH2:23])[CH2:21][CH2:20][CH2:19][CH2:18]2)[CH:12]=1>>[CH3:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH:23][CH2:22][C:17]1([C:13]2[CH:12]=[N:11][CH:16]=[CH:15][CH:14]=2)[CH2:21][CH2:20][CH2:19][CH2:18]1)=[O:6]

Participants

3

Reactant 2

HCID 83732-Methylbenzoic acidHCID 55265176[1-(Pyridin-3-yl)cyclopentyl]methanamine

Product 1

HCID 867162482-Methyl-N-(1-pyridin-3-yl-cyclopentylmethyl)-benzamide

Procedure

From 2-methylbenzoic acid and C-(1-pyridin-3-yl-cyclopentyl)-methylamine. LCMS (MH+): m/z=357.0, tR (minutes, Method B)=1.16

Sources & evidence

ORD record
ord-f75f65de759148b68cd0834160e9ba96
Source dataset
uspto-grants-2015_08
Patent number
US09102591B2

Reaction notes

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