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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 512231Generated: October 30, 2026

2-Fluoro-3-methoxybenzoic acid → N-[4,4-Difluoro-1-(6-fluoro-pyridin-3-yl)-cyclohexylmethyl]-2-fluoro-3-methoxybenzamide

https://huagongshe.com/reaction/512231

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluoro-3-methoxybenzoic acidHCID 3390679—
Reactant[4,4-Difluoro-1-(6-fluoro-pyridin-3-yl)-cyclohexyl]-methylamineHCID 86716261—
ProductN-[4,4-Difluoro-1-(6-fluoro-pyridin-3-yl)-cyclohexylmethyl]-2-fluoro-3-methoxybenzamideHCID 86716266—

Reaction Steps

From 2-fluoro-3-methoxybenzoic acid and C-[4,4-difluoro-1-(6-fluoro-pyridin-3-yl)-cyclohexyl]-methylamine. LCMS (MH+): m/z=397.2, tR (minutes, Method D)=0.69

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09102591B2
Source datasetuspto-grants-2015_08
ORD IDord-f48ee2a9c0e14f37aae3e4390d6a513a
Source noteuspto-grants-2015_08