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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 512232Generated: October 29, 2026

2-Fluoro-5-methoxybenzoic acid → N-[4,4-Difluoro-1-(6-fluoro-pyridin-3-yl)-cyclohexylmethyl]-2-fluoro-5-methoxybenzamide

https://huagongshe.com/reaction/512232

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluoro-5-methoxybenzoic acidHCID 2774543—
Reactant[4,4-Difluoro-1-(6-fluoro-pyridin-3-yl)-cyclohexyl]-methylamineHCID 86716261—
ProductN-[4,4-Difluoro-1-(6-fluoro-pyridin-3-yl)-cyclohexylmethyl]-2-fluoro-5-methoxybenzamideHCID 86716267—

Reaction Steps

From 2-fluoro-5-methoxybenzoic acid and C-[4,4-difluoro-1-(6-fluoro-pyridin-3-yl)-cyclohexyl]-methylamine. LCMS (MH+): m/z=397.1, tR (minutes, Method D)=0.71

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09102591B2
Source datasetuspto-grants-2015_08
ORD IDord-cd1145334ae445c3aa0acf03495dfdb1
Source noteuspto-grants-2015_08