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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 512238Generated: October 26, 2026

2,3-Dichlorobenzoic acid → 2,3-Dichloro-N-[4,4-difluoro-1-(6-trifluoromethyl-pyridin-3-yl)-cyclohexylmethyl]-benzamide

https://huagongshe.com/reaction/512238

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,3-Dichlorobenzoic acidHCID 5765—
Reactant(4,4-Difluoro-1-(6-(trifluoromethyl)pyridin-3-yl)cyclohexyl)methanamineHCID 86716274—
Product2,3-Dichloro-N-[4,4-difluoro-1-(6-trifluoromethyl-pyridin-3-yl)-cyclohexylmethyl]-benzamideHCID 86716273—

Reaction Steps

From 2,3-dichlorobenzoic acid and C-[4,4-difluoro-1-(6-trifluoromethyl-pyridin-3-yl)-cyclohexyl]-methylamine. LCMS (MH+): m/z=467.0, tR (minutes, Method E)=0.83

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09102591B2
Source datasetuspto-grants-2015_08
ORD IDord-452f581875ff4869b690463ab73f3d02
Source noteuspto-grants-2015_08