2,3-Dichlorobenzoic acid → HCID 86716277, compound

HRID 512240Notes

Reaction equation

HRID 512240 reaction equation
[Cl:1][C:2]1[C:10]([Cl:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[F:12][C:13]1([F:29])[CH2:18][CH2:17][C:16]([CH2:27][NH2:28])([C:19]2[CH:20]=[N:21][C:22]([O:25][CH3:26])=[CH:23][CH:24]=2)[CH2:15][CH2:14]1>>[Cl:1][C:2]1[C:10]([Cl:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH:28][CH2:27][C:16]1([C:19]2[CH:20]=[N:21][C:22]([O:25][CH3:26])=[CH:23][CH:24]=2)[CH2:17][CH2:18][C:13]([F:29])([F:12])[CH2:14][CH2:15]1)=[O:6]

Participants

3

Reactant 2

HCID 57652,3-Dichlorobenzoic acidHCID 86716278HCID 86716278, compound

Product 1

HCID 86716277HCID 86716277, compound

Procedure

From 2,3-dichlorobenzoic acid and C-[4,4-difluoro-1-(6-methoxy-pyridin-3-yl)-cyclohexyl]-methylamine. LCMS (MH +) m/z=429.1, tR (minutes, Method D)=0.67

Sources & evidence

ORD record
ord-b4fefcee685e4b619689d69cdf7c88ed
Source dataset
uspto-grants-2015_08
Patent number
US09102591B2

Reaction notes

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