Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 512241Generated: October 25, 2026

2-Cyanobenzoic acid → 2-Cyano-N-[4,4-difluoro-1-(6-trifluoromethyl-pyridin-3-yl)-cyclohexylmethyl]-benzamide

https://huagongshe.com/reaction/512241

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Cyanobenzoic acidHCID 138061—
Reactant(4,4-Difluoro-1-(6-(trifluoromethyl)pyridin-3-yl)cyclohexyl)methanamineHCID 86716274—
Product2-Cyano-N-[4,4-difluoro-1-(6-trifluoromethyl-pyridin-3-yl)-cyclohexylmethyl]-benzamideHCID 86716279—

Reaction Steps

From 2-cyanobenzoic acid and C-[4,4-difluoro-1-(6-trifluoromethyl-pyridin-3-yl)-cyclohexyl]-methylamine. LCMS (MH+): m/z=424.2, tR (minutes, Method D)=0.66

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09102591B2
Source datasetuspto-grants-2015_08
ORD IDord-802e565d90ef435098fd665ad4db6690
Source noteuspto-grants-2015_08