2,3-Dichlorobenzoic acid → HCID 86716281, compound

HRID 512243Notes

Reaction equation

HRID 512243 reaction equation
[Cl:1][C:2]1[C:10]([Cl:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[CH:12]1([CH:15]([C:18]2[CH:19]=[N:20][C:21]([C:24]([F:27])([F:26])[F:25])=[CH:22][CH:23]=2)[CH2:16][NH2:17])[CH2:14][CH2:13]1>>[Cl:1][C:2]1[C:10]([Cl:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH:17][CH2:16][CH:15]([CH:12]1[CH2:14][CH2:13]1)[C:18]1[CH:19]=[N:20][C:21]([C:24]([F:27])([F:25])[F:26])=[CH:22][CH:23]=1)=[O:6]

Participants

3

Reactant 2

HCID 57652,3-Dichlorobenzoic acidHCID 86716187HCID 86716187, compound

Product 1

HCID 86716281HCID 86716281, compound

Procedure

From 2,3-dichlorobenzoic acid and 2-cyclopropyl-2-(6-trifluoromethyl-pyridin-3-yl)-ethylamine. LCMS (MH+): m/z=403.1, tR (minutes, Method D)=0.79

Sources & evidence

ORD record
ord-4cef36e39ad340a589ba12de3eb038b1
Source dataset
uspto-grants-2015_08
Patent number
US09102591B2

Reaction notes

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