2,3-Dichlorobenzoic acid → HCID 86716282, compound

HRID 512244Notes

Reaction equation

HRID 512244 reaction equation
[Cl:1][C:2]1[C:10]([Cl:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[F:12][C:13]1([F:28])[CH2:18][CH2:17][C:16]([CH2:26][NH2:27])([C:19]2[CH:20]=[N:21][CH:22]=[C:23]([F:25])[CH:24]=2)[CH2:15][CH2:14]1>>[Cl:1][C:2]1[C:10]([Cl:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH:27][CH2:26][C:16]1([C:19]2[CH:20]=[N:21][CH:22]=[C:23]([F:25])[CH:24]=2)[CH2:17][CH2:18][C:13]([F:12])([F:28])[CH2:14][CH2:15]1)=[O:6]

Participants

3

Reactant 2

HCID 57652,3-Dichlorobenzoic acidHCID 86716283HCID 86716283, compound

Product 1

HCID 86716282HCID 86716282, compound

Procedure

From 2,3-dichlorobenzoic acid and C-[4,4-difluoro-1-(5-fluoro-pyridin-3-yl)-cyclohexyl]-methylamine. LCMS (MH+): m/z=417.2, tR (minutes, Method D)=0.68

Sources & evidence

ORD record
ord-d191a8e81b814625a55af6a382421613
Source dataset
uspto-grants-2015_08
Patent number
US09102591B2

Reaction notes

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