2,3-Dichlorobenzoic acid → HCID 86716298, compound

HRID 512257Notes

Reaction equation

HRID 512257 reaction equation
[Cl:1][C:2]1[C:10]([Cl:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[CH3:12][C:13]1[N:18]=[CH:17][C:16]([CH:19]([CH2:22][C:23]2([C:26]([F:29])([F:28])[F:27])[CH2:25][CH2:24]2)[CH2:20][NH2:21])=[CH:15][N:14]=1>>[Cl:1][C:2]1[C:10]([Cl:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH:21][CH2:20][CH:19]([C:16]1[CH:17]=[N:18][C:13]([CH3:12])=[N:14][CH:15]=1)[CH2:22][C:23]1([C:26]([F:27])([F:28])[F:29])[CH2:25][CH2:24]1)=[O:6]

Participants

3

Reactant 2

HCID 57652,3-Dichlorobenzoic acidHCID 86716299HCID 86716299, compound

Product 1

HCID 86716298HCID 86716298, compound

Procedure

From 2,3-dichlorobenzoic acid and 2-(2-methyl-pyrimidin-5-yl)-3-(1-trifluoromethyl-cyclopropyl)-propylamine. LCMS (MH+): m/z=377.1, tR (minutes, Method F)=1.68

Sources & evidence

ORD record
ord-2dcce7944d594738baaf4515304177cc
Source dataset
uspto-grants-2015_08
Patent number
US09102591B2

Reaction notes

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