2,3-Dichlorobenzoic acid → HCID 86716305, compound

HRID 512261Notes

Reaction equation

HRID 512261 reaction equation
[Cl:1][C:2]1[C:10]([Cl:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[F:12][C:13]([F:31])([F:30])[C:14]1[N:19]=[CH:18][C:17]([CH:20]([CH2:23][C:24]2([CH:27]([F:29])[F:28])[CH2:26][CH2:25]2)[CH2:21][NH2:22])=[CH:16][CH:15]=1>>[Cl:1][C:2]1[C:10]([Cl:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH:22][CH2:21][CH:20]([C:17]1[CH:18]=[N:19][C:14]([C:13]([F:31])([F:12])[F:30])=[CH:15][CH:16]=1)[CH2:23][C:24]1([CH:27]([F:28])[F:29])[CH2:25][CH2:26]1)=[O:6]

Participants

3

Reactant 2

HCID 57652,3-Dichlorobenzoic acidHCID 86716306HCID 86716306, compound

Product 1

HCID 86716305HCID 86716305, compound

Procedure

From 2,3-dichlorobenzoic acid and 2-(6-trifluoromethyl-pyridin-3-yl)-3-(1-difluoromethyl-cyclopropyl)-propylamine. LCMS (MH+): m/z=467.1, tR (minutes, Method G)=2.62

Sources & evidence

ORD record
ord-7addc7f690984aedb083850b34b2fd3c
Source dataset
uspto-grants-2015_08
Patent number
US09102591B2

Reaction notes

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