2-Fluorobenzoic acid → HCID 86716308, compound

HRID 512263Notes

Reaction equation

HRID 512263 reaction equation
[F:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[CH:11]1([C:14]2[N:19]=[CH:18][C:17]([CH:20]([CH2:23][C:24]3([C:27]([F:30])([F:29])[F:28])[CH2:26][CH2:25]3)[CH2:21][NH2:22])=[CH:16][CH:15]=2)[CH2:13][CH2:12]1>>[CH:11]1([C:14]2[N:19]=[CH:18][C:17]([CH:20]([CH2:23][C:24]3([C:27]([F:30])([F:28])[F:29])[CH2:26][CH2:25]3)[CH2:21][NH:22][C:4](=[O:6])[C:3]3[CH:7]=[CH:8][CH:9]=[CH:10][C:2]=3[F:1])=[CH:16][CH:15]=2)[CH2:12][CH2:13]1

Participants

3

Reactant 2

HCID 99352-Fluorobenzoic acidHCID 86716302HCID 86716302, compound

Product 1

HCID 86716308HCID 86716308, compound

Procedure

From 2-fluorobenzoic acid and 2-(6-cyclopropyl-pyridin-3-yl)-3-(1-trifluoromethyl-cyclopropyl)-propylamine. LCMS (MH+): m/z=407.1, tR (minutes, Method G)=2.01

Sources & evidence

ORD record
ord-3224eba98ee04d04996c05f10250b503
Source dataset
uspto-grants-2015_08
Patent number
US09102591B2

Reaction notes

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