2-Fluorobenzoic acid → HCID 86716310, compound

HRID 512267Notes

Reaction equation

HRID 512267 reaction equation
[F:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[F:11][C:12]([F:31])([F:30])[C:13]1([CH2:16][CH:17]([C:20]2[CH:21]=[N:22][C:23]([C:26]([F:29])([F:28])[F:27])=[CH:24][CH:25]=2)[CH2:18][NH2:19])[CH2:15][CH2:14]1>>[F:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH:19][CH2:18][CH:17]([C:20]1[CH:21]=[N:22][C:23]([C:26]([F:29])([F:27])[F:28])=[CH:24][CH:25]=1)[CH2:16][C:13]1([C:12]([F:11])([F:30])[F:31])[CH2:14][CH2:15]1)=[O:6]

Participants

3

Reactant 2

HCID 99352-Fluorobenzoic acidHCID 86716300HCID 86716300, compound

Product 1

HCID 86716310HCID 86716310, compound

Procedure

From 2-fluorobenzoic acid and 3-(1-trifluoromethyl-cyclopropyl)-2-(6-trifluoromethyl-pyridin-3-yl)-propylamine. LCMS (MH+): m/z=435.1, tR (minutes, Method G)=2.58

Sources & evidence

ORD record
ord-24a3c5443b00402da179a37360442176
Source dataset
uspto-grants-2015_08
Patent number
US09102591B2

Reaction notes

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