2,3-Dichlorobenzoic acid → HCID 86716313, compound

HRID 512269Notes

Reaction equation

HRID 512269 reaction equation
[Cl:1][C:2]1[C:10]([Cl:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[F:12][C:13]1([F:28])[CH2:18][CH2:17][C:16]([CH2:26][NH2:27])([C:19]2[CH:20]=[N:21][C:22]([CH3:25])=[N:23][CH:24]=2)[CH2:15][CH2:14]1>>[Cl:1][C:2]1[C:10]([Cl:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH:27][CH2:26][C:16]1([C:19]2[CH:24]=[N:23][C:22]([CH3:25])=[N:21][CH:20]=2)[CH2:17][CH2:18][C:13]([F:12])([F:28])[CH2:14][CH2:15]1)=[O:6]

Participants

3

Reactant 2

HCID 57652,3-Dichlorobenzoic acidHCID 86716312HCID 86716312, compound

Product 1

HCID 86716313HCID 86716313, compound

Procedure

From 2,3-dichlorobenzoic acid and C-[4,4-difluoro-1-(2-methyl-pyrimidin-5-yl)-cyclohexyl]-methylamine. LCMS (MH+): m/z=414.1, tR (minutes, Method F)=2.57

Sources & evidence

ORD record
ord-9155944adfbd4fc9a3c80051013b1adf
Source dataset
uspto-grants-2015_08
Patent number
US09102591B2

Reaction notes

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