2,3-Dichlorobenzoic acid → HCID 86716316, compound

HRID 512271Notes

Reaction equation

HRID 512271 reaction equation
[Cl:1][C:2]1[C:10]([Cl:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[NH2:12][CH2:13][C:14]1([C:22]2[CH:23]=[CH:24][C:25]([C:28]([OH:31])([CH3:30])[CH3:29])=[N:26][CH:27]=2)[CH2:19][CH2:18][C:17]([F:21])([F:20])[CH2:16][CH2:15]1>>[Cl:1][C:2]1[C:10]([Cl:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH:12][CH2:13][C:14]1([C:22]2[CH:27]=[N:26][C:25]([C:28]([OH:31])([CH3:29])[CH3:30])=[CH:24][CH:23]=2)[CH2:19][CH2:18][C:17]([F:21])([F:20])[CH2:16][CH2:15]1)=[O:6]

Participants

3

Reactant 2

HCID 57652,3-Dichlorobenzoic acidHCID 86716317HCID 86716317, compound

Product 1

HCID 86716316HCID 86716316, compound

Procedure

From 2,3-dichlorobenzoic acid and 2-[5-(1-aminomethyl-4,4-difluoro-cyclohexyl)-pyridin-2-yl]-propan-2-ol. LCMS (MH+): m/z=457.1, tR (minutes, Method F)=1.97

Sources & evidence

ORD record
ord-d7cb7bdb19594f79830818e6a2041097
Source dataset
uspto-grants-2015_08
Patent number
US09102591B2

Reaction notes

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