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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 512273Generated: October 30, 2026

2-Chloro-3-methoxybenzoic acid → 2-chloro-N-[3-cyclopropyl-2-[6-(trifluoromethyl)-3-pyridyl]propyl]-3-methoxybenzamide

https://huagongshe.com/reaction/512273

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-3-methoxybenzoic acidHCID 16218063—
Reactant3-Cyclopropyl-2-(6-trifluoromethyl-pyridin-3-yl)-propylamineHCID 86716284—
Product2-chloro-N-[3-cyclopropyl-2-[6-(trifluoromethyl)-3-pyridyl]propyl]-3-methoxybenzamideHCID 73673067—

Reaction Steps

From 2-chloro-3-methoxybenzoic acid and 3-cyclopropyl-2-(6-(trifluoromethyl)pyridin-3-yl)propan-1-amine. LCMS (MH+): m/z=413.1, tR (minutes, Method G)=2.84

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09102591B2
Source datasetuspto-grants-2015_08
ORD IDord-630ffed1157946a09bf324ffe891c039
Source noteuspto-grants-2015_08