Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 512284Generated: October 30, 2026

2-Chloro-3-fluorobenzoic acid → 2-chloro-3-fluoro-N-(2-(4-chlorophenyl)-2-(tetrahydro-2H-pyran-4-yl)ethyl)benzamide

https://huagongshe.com/reaction/512284

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-3-fluorobenzoic acidHCID 302620—
Reactant2-(4-chlorophenyl)-2-(tetrahydro-2H-pyran-4-yl)ethanamineHCID 83561213—
Product2-chloro-3-fluoro-N-(2-(4-chlorophenyl)-2-(tetrahydro-2H-pyran-4-yl)ethyl)benzamideHCID 86716329—

Reaction Steps

From 2-chloro-3-fluorobenzoic acid and 2-(4-chlorophenyl)-2-(tetrahydro-2H-pyran-4-yl)ethanamine. LCMS (MH+): m/z=396.1, tR (minutes, Method G)=2.36

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09102591B2
Source datasetuspto-grants-2015_08
ORD IDord-463af01ba9fa4361b8f8e91021667d3c
Source noteuspto-grants-2015_08